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Transforming Tomorrow, Today
Published by the National Brain Tumor Society, this monthly newsletter includes updates on our integrated research, advocacy, and public policy programs, as well as upcoming events across the nation and in your community.

September 2013

Great New Resource on Brain Tumors

Frankly Speaking About Cancer: Brain Tumors

A big thanks to our partner Cancer Support Community for working with us to create this amazing new resource for patients, families, and caregivers, Frankly Speaking about Cancer: Brain Tumors.

This 96 page book is full of helpful information, tips, and resources. Download your copy today.

Research Spotlight: Dr. David Louis

Dr. David Louis, Pathologist-in-Chief at Massachusetts General Hospital (MGH) and Benjamin Castleman Professor of Pathology at Harvard Medical School, is an internationally recognized expert in brain tumor pathology and molecular genetics. In addition to his prestigious work, Dr. Louis was recently named one of the two (initial) grant recipients for the National Brain Tumor Society Oligodendroglioma Research Fund, and will be named as the 2013 Feldman Founders award recipient at our upcoming Annual Meeting.

In anticipation of accepting this award, Dr. Louis graciously agreed to answer a few questions about his contributions to the field of brain tumor research:

Can you discuss how your earlier findings in glioblastoma multiforme (GBM) have informed your current work in oligodendrogliomas?

I have worked with Drs. Mario Suva and Brad Bernstein to study GBM at the “epigenetic” level (i.e., the level at which genes are controlled). Through these studies, Dr. Suva has clarified a set of control factors (transcription factors) that seem to be responsible for making a GBM stem cell have its particularly aggressive features. We are now using epigenetics to study oligodendrogliomas.

What is your hope for your current oligodendroglioma work. How do you see it moving the field forward toward better solutions for patients?

The eventual behavior of tumor cells relates to how their proteins act. Protein activity is increased when genes are activated. Epigenetics is a field that studies how genes are activated and inactivated. Therefore, the study of the epigenetic landscape of oligodendrogliomas will give us knowledge about what changes control the molecules which make cells cancerous. From a treatment point of view, it is exciting that epigenetic changes may be more straightforward to manipulate for therapeutic ends than are genetic mutations.

The eventual behavior of tumor cells relates to how their proteins act. Protein activity is increased when genes are activated. Epigenetics is a field that studies how genes are activated and inactivated. Therefore, the study of the epigenetic landscape of oligodendrogliomas will give us knowledge about what changes control the molecules which make cells cancerous. From a treatment point of view, it is exciting that epigenetic changes may be more straightforward to manipulate for therapeutic ends than are genetic mutations.

Read the full Q&A with Dr. Louis here.

Watch our State of Research Breakfast Live

Summit 2013

The State of Research Breakfast at our 2013 Summit will be available by live webcast on Friday, October 4 at 8:30 AM EST.

Join us and hear about the current state of brain tumor research from National Brain Tumor Society leadership and experts in the field, and how we are using the knowledge to drive transformational change. Learn more.

 

Thank you for all your support and help in building awareness during Childhood Cancer Awareness month!

 

Community Events Update

Race for the Brain
Columbus, OH - 10/6
Join this fun 5K run and walk at the Hoover Reservoir. Sign up now.

Find an upcoming event or email communityevents@braintumor.org to start your own community event. Get involved today!

Donate Now

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2013 Events

Unite with us in the fight against brain tumors - Participate in an event near you!

Boston, MA - 10/3
2013 Summit

Boston, MA - 10/6
Boston Brain Tumor Walk

Los Angeles - 10/19
Los Angeles Brain Tumor Walk

NEW San Jose, CA - 10/26
Silicon Valley Brain Tumor Walk

Philadelphia, PA - 11/3
Race for Hope - Philadelphia

Fort Worth, TX - 11/9
Dallas Ft. Worth Brain Tumor Walk

See all events

Read our latest Public Policy & Advocacy Update here

Tulips Against Tumors

In the Brain Tumor Community

3rd Annual Brain Tumor Symposium: Current Innovations in Brain Tumor Treatments
Philadelphia, PA - 11/1
Learn more

Recent Articles

Nanodiamonds Used to Deliver Drugs Into Brain Tumors

New Laser-based Tool Could Dramatically Improve the Accuracy of Brain Tumor Surgery

More research news

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National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels.

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